dPKR kinase domain phosphorylated on residue T446 akin to chain B on the PKR kinase – eIF2? crystal structure PDB ID 2A19. seventeen autophosphorylation at T466 isn't feasible in this geometry and the docking web page on helix ?G for that substrate eIF2? is blocked. nevertheless, similar interfaces making use of the ?EF and ?G helices are descri